SS-31

SS-31 (Elamipretide) is a synthetic mitochondrial-targeting peptide studied in research settings for its role in supporting mitochondrial membrane integrity, oxidative stress modulation, and cellular energy regulation pathways. In simple terms, researchers use SS-31 to better understand how protecting mitochondrial structure can influence cellular energy production and resilience under conditions of metabolic or oxidative stress in controlled laboratory models.

From a technical standpoint, SS-31 is a tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) designed to selectively localize to the inner mitochondrial membrane, where it interacts with cardiolipin, a phospholipid essential for maintaining mitochondrial structure and electron transport chain efficiency. Research has focused on its effects on reducing mitochondrial reactive oxygen species (ROS), stabilizing membrane potential, and supporting ATP production pathways in preclinical models.

In laboratory studies, SS-31 is commonly evaluated within mitochondrial biology and cellular energy research, particularly in contexts involving oxidative stress, age-related mitochondrial dysfunction models, and metabolic efficiency studies. Its mechanism of action is centered on mitochondrial protection rather than receptor-mediated hormonal signaling, making it distinct from endocrine or growth factor peptides.

SS-31 is intended strictly for laboratory research purposes only and is not approved for human consumption, medical use, or diagnostic applications.

Key Research Areas

• Mitochondrial membrane stability and cardiolipin interaction
• Oxidative stress and reactive oxygen species (ROS) reduction models
• ATP production and cellular energy efficiency
• Mitochondrial dysfunction and aging-related research models
• Electron transport chain support mechanisms

Chemical Information

• Compound Name: SS-31 (Elamipretide)
• Type: Synthetic mitochondrial-targeting tetrapeptide
• Sequence: D-Arg-Dmt-Lys-Phe-NH₂
• Mechanism: Mitochondrial inner membrane (cardiolipin-binding) peptide
• Research Focus: Mitochondrial function and cellular energy regulation

Important Notice

This compound is sold strictly for laboratory research purposes only. It is not intended for human consumption, medical treatment, or diagnostic use. Proper handling and regulatory compliance are required by the purchaser.